Aggravated visual toxicity of eco-corona on micro(nano)plastics in marine medaka (Oryzias melastigma)

Published in Environmental Science & Technology Letters, 2025

We evaluate how eco-corona (biomolecule coatings formed in seawater) modifies the physicochemical properties of MNPs and enhances visual toxicity in Oryzias melastigma.

  • Findings: eye malformation, retinal histopathology, increased apoptosis, and downregulated vision-related gene expression are more severe with eco-corona–modified MNPs.
  • Implication: environmental transformations (eco-corona/plastisphere) must be considered in ecological risk assessment of MNPs.

Project/news pages summarizing outcomes are available; official DOI pending in this entry—add when available.

Recommended citation: Ma Y, Liu L*, Xu Y, Feng J, Wang C, Liu B, Lin P, Yin H, Sun L, Li P, Li Z-H*. (2025). Aggravated visual toxicity of eco-corona on micro(nano)plastics in marine medaka (Oryzias melastigma). Environmental Science & Technology Letters, 12(5):510–517.
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