Neurobehavioral toxicity induced by combined exposure of micro/nanoplastics and triphenyltin in marine medaka (Oryzias melastigma)

Published in Environmental Pollution, 2024

We perform a co-exposure study integrating behavior assays, biochemical endpoints, and gene expression analyses to evaluate interactive toxicity of MNPs + TPT during early development in Oryzias melastigma.

  • Behavior: locomotor and light–dark preference alterations indicate neurotoxicity.
  • Biochemical: oxidative stress markers and AChE activity disruption.
  • Molecular: differential expression of neuronal and stress-response genes.

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Recommended citation: Lin P, Liu L, Ma Y, Du R, Yi C, Li P, Xu Y, Yin H, Sun L, Li Z-H. (2024). Neurobehavioral toxicity induced by combined exposure of micro/nanoplastics and triphenyltin in marine medaka (Oryzias melastigma). Environmental Pollution, 356:124334.
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